Trap-Free 2D 液相四極桿質譜儀

Trap-Free 2D LC/MS system for Quadrupole LCMS

提問:
原本 LC 分析條件是使用非揮發性移動相偵測器為紫外線 (UV) 來檢測不純物,當轉換到 LCMS 系統測定時是否需要調整方法改以使用揮發性移動相?

答:
使用 Trap-free 2D LCMS 系統,流動相可以直接置換 (online),因此不需額外進行的方法開發。

  • 系統直接置換 (online) 非揮發性流動相和揮發性流動相。
  • LabSolutions 軟體裡的支援工具。
  • 只將目標雜質導入 MS 系統,因此無需擔心層析峰錯置。

使用支持工具建立時間程序和批次處理表

輸入在一維 UV 層析圖中觀察到的雜質峰滯留時間,可以計算最合適的閥切換時間,並建立新的批次處理表來獲得多種雜質及其各自空白樣品的相關數據。

使用數據瀏覽器可以輕鬆鑑別不純物

數據瀏覽器中顯示樣品和空白數據的範例。

備註和注意事項

  1. Trap-Free 2D LCMS 系統是一個應用系統,配置有 LC 單元、四極桿質譜儀和啟動套組。
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